PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya.
Identifieur interne : 001615 ( Main/Exploration ); précédent : 001614; suivant : 001616PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya.
Auteurs : Xuejian Xiong [Canada] ; Hongyan Song ; Tuan On ; Lucas Lochovsky ; Nicholas J. Provart ; John ParkinsonSource :
- Bioinformatics (Oxford, England) [ 1367-4811 ] ; 2011.
English descriptors
- KwdEn :
- MESH :
- classification : Eukaryota.
- genetics : Eukaryota.
- methods : Computational Biology, Genomics.
- Biological Evolution, Cluster Analysis, Internet, Phylogeny, Programming Languages, User-Computer Interface.
Abstract
With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionary trajectories of user-defined subsets of model organism genes. Applied to pathways or complexes, PhyloPro allows the user to rapidly identify core conserved elements of biological processes together with those that may represent lineage-specific innovations. PhyloPro thus provides a valuable resource for the evolutionary and comparative studies of biological systems.
DOI: 10.1093/bioinformatics/btr023
PubMed: 21252074
Affiliations:
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Le document en format XML
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Provart</name></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2011">2011</date><idno type="RBID">pubmed:21252074</idno><idno type="pmid">21252074</idno><idno type="doi">10.1093/bioinformatics/btr023</idno><idno type="wicri:Area/PubMed/Corpus">000C32</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C32</idno><idno type="wicri:Area/PubMed/Curation">000C32</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C32</idno><idno type="wicri:Area/PubMed/Checkpoint">000C32</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000C32</idno><idno type="wicri:Area/Ncbi/Merge">000E12</idno><idno type="wicri:Area/Ncbi/Curation">000E12</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E12</idno><idno type="wicri:Area/Main/Merge">001681</idno><idno type="wicri:Area/Main/Curation">001615</idno><idno type="wicri:Area/Main/Exploration">001615</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya.</title><author><name sortKey="Xiong, Xuejian" sort="Xiong, Xuejian" uniqKey="Xiong X" first="Xuejian" last="Xiong">Xuejian Xiong</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children</wicri:regionArea><wicri:noRegion>Hospital for Sick Children</wicri:noRegion></affiliation></author><author><name sortKey="Song, Hongyan" sort="Song, Hongyan" uniqKey="Song H" first="Hongyan" last="Song">Hongyan Song</name></author><author><name sortKey="On, Tuan" sort="On, Tuan" uniqKey="On T" first="Tuan" last="On">Tuan On</name></author><author><name sortKey="Lochovsky, Lucas" sort="Lochovsky, Lucas" uniqKey="Lochovsky L" first="Lucas" last="Lochovsky">Lucas Lochovsky</name></author><author><name sortKey="Provart, Nicholas J" sort="Provart, Nicholas J" uniqKey="Provart N" first="Nicholas J" last="Provart">Nicholas J. Provart</name></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name></author></analytic><series><title level="j">Bioinformatics (Oxford, England)</title><idno type="eISSN">1367-4811</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biological Evolution</term><term>Cluster Analysis</term><term>Computational Biology (methods)</term><term>Eukaryota (classification)</term><term>Eukaryota (genetics)</term><term>Genomics (methods)</term><term>Internet</term><term>Phylogeny</term><term>Programming Languages</term><term>User-Computer Interface</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Eukaryota</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Eukaryota</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Computational Biology</term><term>Genomics</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biological Evolution</term><term>Cluster Analysis</term><term>Internet</term><term>Phylogeny</term><term>Programming Languages</term><term>User-Computer Interface</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionary trajectories of user-defined subsets of model organism genes. Applied to pathways or complexes, PhyloPro allows the user to rapidly identify core conserved elements of biological processes together with those that may represent lineage-specific innovations. PhyloPro thus provides a valuable resource for the evolutionary and comparative studies of biological systems.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Lochovsky, Lucas" sort="Lochovsky, Lucas" uniqKey="Lochovsky L" first="Lucas" last="Lochovsky">Lucas Lochovsky</name><name sortKey="On, Tuan" sort="On, Tuan" uniqKey="On T" first="Tuan" last="On">Tuan On</name><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><name sortKey="Provart, Nicholas J" sort="Provart, Nicholas J" uniqKey="Provart N" first="Nicholas J" last="Provart">Nicholas J. Provart</name><name sortKey="Song, Hongyan" sort="Song, Hongyan" uniqKey="Song H" first="Hongyan" last="Song">Hongyan Song</name></noCountry><country name="Canada"><noRegion><name sortKey="Xiong, Xuejian" sort="Xiong, Xuejian" uniqKey="Xiong X" first="Xuejian" last="Xiong">Xuejian Xiong</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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